Subcellular fractionation and separation is an important yet complicated process. The enrichment of subcellular compartments followed by the identification of their protein contents by proteomics or other methods is a powerful method for protein localization and functional studies. This will ultimately increase the capability to comprehensively understand the organellar as well as global proteome and thereby will be a significant tool for molecular biological research.

Subcellular services leveraging Edge Technology, combined with Edge 200 Separation System, provide a powerful, orthogonal and reproducible subcellular fractionation and separation, and include:

• Tissue and cell homogenization
• Generation of nuclear fraction and post-nuclear supernatant (PNS)
• Reproducible subcellular fractionation using Edge 200 Separation System
• Organelle separation and enrichment


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